Clermont, who currently top the Top14 and are undefeated in European competition this season, recall the likes of French international Wesley Fofana for the big Round 4 clash as they bid to remain top of Pool 1 (kick-off 1pm GMT).
Eight full French internationals feature in the match day squad with talented half back duo Camille Lopez and Scottish scrum half Greig Laidlaw again joining forces.
Clermont will again by captained by back row Fritz Lee.
ASM Clermont Auvergne: Isaia Toeava, Peter Betham, Apisai Naqalevu, Wesley Fofana, Remy Grosso, Camille Lopez, Greig Laidlaw; Loni Uhila, Yohan Beheregaray, Michael Simutoga, Paul Jedrasiak, Sebastien Vahaamahina, Arthur Iturria, Judicael Cancoriet, Fritz Lee (c)
Replacements:John Ulugia, Etienne Falgoux, Sipili Falatea, Sitaleki Timani, Maxence Lemardelet, Charlie Cassang, Patricio Fernandez, Damian Penaud