Dragons have named their starting line-up for the clash as the team prepares for the forthcoming Celtic Cup - that kicks off next Friday on home soil against Cardiff Blues.
Fly half Arwel Robson will make a playing return in the clash, after recovering from an ankle injury, while Zane Kirchner will get game time at outside centre.
Supporters are advised that entry to the game at Ystrad Mynach will be FREE to Season Ticket holders and juniors and £5 for adults.
Dragons A (v Ospreys Development): Will Talbot-Davies, George Gasson, Zane Kirchner, Connor Edwards (c), Deon Smith, Arwel Robson, Dan Babos; Gerard Ellis, Rhys Lawrence, Chris Coleman, Joe Davies, Max Williams, Lennon Greggains, James Benjamin, Taine Basham.
Replacements: Zac Hewlett, Josh Reynolds, Luke Yendle, Ed Scragg, Ben Fry, Dafydd Buckland, Jacob Botica, Joe Goodchild, Tiaan Loots, David Richards, Carwyn Penny.