The Dragons will take on the Cardiff Blues in the RaboDirect Pro 12 league, at Cardiff Arms Park on Boxing Day at 2.05pm.
New look back row sees skipper Lewis Evans move to blindside whilst Nic Cudd starts at openside; Faletau then finishes off the trio at number eight, after returning from starting all Welsh Autumn tests.
Hooker Sam Parry gets the nod at two, after an impressive first 40 minutes against Mogliano at Rodney Parade. Sam was taken off at half time, after suffering a dead leg but has now recovered to start in this Christmas Derby.
Dragons Team to take on the Blues
Hallam Amos, Will Harries, Pat Leach, Andy Tuilagi, Mike Poole, Dan Evans, Wayne Evans; Phil Price, Sam Parry, Dan Way, Andrew Coombs, Rob Sidoli, Lewis Evans © Nic Cudd, Toby Faletau.
Replacements:
Hugh Gustafson, Owen Evans, Nathan Buck, Adam Jones, Tom Brown, Jonathan Evans, Lewis Robling, Jack Dixon
